Bio-Stimulators / Bio-Remodelling

PROFHILO Bio-remodelling – for skin laxity

What is Profhilo® treatment

Profhilo is the first BDDE-free stabilised injectable hyaluronic acid (HA) based product for treating skin laxity. With one of the highest concentrations of HA on the market (64mg / 2ml) it is not only boosting and hydrating the skin, but also remodels the ageing and sagging tissue. Profhilo delivers great results as a treatment on its own or in combination with other aesthetics treatments currently on offer.

Profhilo® treatment can help to:

  • Increase skin firmness and elasticity
  • Tighten and lift skin
  • Improve skin tone and texture
  • Rehydrate skin
  • Restore radiance


There are many characteristics that make Profhilo unique from anything else available on the market right now. There is no BDDE content. It is thermally cross-linked generating stabilised hybrid co-operative complexes of H-HA and L-HA. Despite its high HA content, it has a low inflammatory profile coupled with pro-healing properties backed by clinical studies.

In Profhilo, L-HA is released slowly from the HA hybrid complexes and therefore does not trigger the first inflammatory cytokines making it very biocompatible. It also increases patient comfort during and after treatment and provides hydration to the skin especially in the epidermis – the Hydro effect.

H-HA in Profhilo provides a stable HA architecture in the dermis. This gives a volumetric effect – the Lift effect.

Another advantage of the stable co-operative hybrid complex when compared to H-HA and L-HA is the increase in the expression levels of type I and type III collagen in fibroblast and type IV and VII collagen in keratinocytes.

This results in improved skin quality and skin hydration both in the dermis and epidermis. There is also increased production of endogenous HA and elastin giving the skin a more youthful look.

Profhilo is developed by using a patented technology resulting in hybrid cooperative complexes between high molecular weight HA and low molecular HA without the use of any chemical cross-linking compounds. These complexes increase the stability of HA to enzymatic and mechanical degradation.

As a stabilised product Profhilo lasts in the skin around 28 days. During this time the stimulation of 4 different types of collagen and elastin takes place by slow release of HA. The stimulation results in significant tissue improvement. Therefore, we cannot say that Profhilo is a skin booster as it also has a significant tightening / lifting effect on the tissue.

The downtime is minimal. After the treatment, it is recommended to avoid physical strain and sports for 24 hours. Please also avoid having further cosmetic procedures for 48 hours. It is not recommended to have sauna or steamy bath for the first few days either. It’s best to stay out of the sun if any bruising or prolonged swelling occurs.

 To achieve the best long-lasting results, two treatments are recommended with a four-week interval. Some people may see the results within first week, but the best outcomes of the treatment will be visible four weeks after the second treatment.

Compared to dermal fillers, Profhilo enhances stem cell reproduction meaning your skin rejuvenates. It restores both skin and fat layers to their natural state, and stimulates the body to produce four collagen types. Unlike dermal fillers it does not provide volume.

Usually 2 treatments are recommended (one month apart). You will notice a difference as soon as Profhilo is injected. However optimum results can take up to 2 weeks, where you will by invited for a review and follow-up.

Profhilo generally lasts for up to 6 months where you will experience increased firmness, elasticity and an overall improved quality of skin. At six month you will be invited for a further session to maintain the quality of your skin.

45 Minutes

Neck

£ 500 – 2 treatments 4 weeks apart

Face

 £ 500 – 2 treatments 4 weeks apart

Top up (within 6 months)

£ 200 per vial

NucleoFILL

NucleoFILL is a preparation for deep skin renewal and bio-restructuring. This innovative treatment works on three levels: lifting, antioxidation and hydration.

It is a unique, triple action at the cellular level, which gives the effect of a clear and long-lasting rejuvenation. NucleoFILL is a synonym for innovative biotechnology in aesthetic medicine and anti-aging. This scientifically proven method of skin bio stimulation contains polynucleotides that stimulate the skin to rebuild in a three-way mechanism.

The first course of action is the receptors on fibroblasts in the skin. Thanks to such stimulation, they transform into myofibroblasts. The process of the production of type I collagen and elastin is stimulated, which causes the skin to thicken and lift. The second mechanism is the “scavenging” of free radicals and antioxidant activity. Polynucleotides bind water and ensure long-term iso-osmotic hydration of the extracellular matrix. As a result, the skin becomes moisturized and supple.

  • hypoxic skin
  • skin exposed to oxidative stress
  • dehydrated skin
  • stretch marks and scars

 

In order to obtain the best results, NucleoFILL is performed in a series of 3-4 treatments every 2-4 weeks.

NucleoFILL comes in two forms: NucleoFILL Medium – contains 1.5ml of 2% polynucleotide and NucleoFILL Strong – contains 1.5ml of 2.5% polynucleotide.

45 Minutes

NucleoFILL Medium-application of one ampoule £ 195 Each subsequent treatment in the series 10% discount – £ 175

NucleoFILL Strong-application of one ampoule £ 225 Each subsequent treatment in the series 10% discount- £ 200

NucleoFILL Medium and NucleoFILL Strong combined therapy – application of one ampoule of NucleoFILL Medium plus application of one ampule of NucleoFILL Strong £ 310 (Each subsequent treatment in the series 10% discount – £ 280)

Some patients may require combination therapy, i.e. the Strong dose is applied to the middle of the face and the Medium dose is applied to the lower face and chin or neck. Such therapy allows for better effects and simultaneous treatment of the face and neck.

SuneKos

Ideal for those who want to restore the naturally youthful look of your skin and improve signs of ageing, SuneKos is an injectable treatment that’s entirely different to filler treatments; this treatment uses a patented formula which combines amino acids (the essential building blocks of elastin and collagen) with hyaluronic acid. SuneKos regenerates the Extra Cellular Matrix (ECM) of your skin and deeply hydrates and plumps the treated tissue. This leads to ‘dermal biogenesis’. The result? A reduction in the severity of your wrinkles, hydration to both the superficial and deep layers of your skin, a desirable volumising effect and a dramatic boost to your elastin and collagen.

This treatment is ideal if you have loose, crepey, thin skin and/or a loss of volume around your eyes. It is also suited to help with lines, wrinkles, crepiness, volume-loss and laxity on your neck and face. SuneKos can significantly regenerate your ageing skin and restore a natural-looking, youthful appearance.

At the Simply Skin Clinic the SuneKos procedure is performed only by medical practitioners.

Winner of the Safety in Beauty Innovation and Pioneering award 2019, SuneKos is a non-surgical treatment comprising of a unique combination of hyaluronic acid and amino acids which triggers a skin regeneration process called dermal biogenesis. 

Whilst deeply hydrating and plumping the skin, clinical trials have shown that the Hyaluronic Acid (HA) can activate bio-revitalisation from within your skin which results in plumper, smoother, firmer, more youthful-looking skin. SuneKos combines this HA with a special combination of amino acids which directly stimulates the Extra Cellular Matrix (ECM) fibroblasts which in turn rebuilds the living layer of your skin, called the dermis.

There are two types of SuneKos; SuneKos 200 and SuneKos 1200. SuneKos 200 is used to treat around the eyes, face, neck, chest and hands and is perfect for earlier signs of ageing. SuneKos 1200 is used in conjunction with SuneKos 200 if your skin needs extra structural support to improve sagging skin or if you have deeper, more advanced wrinkles. Your specific requirements will be assessed and discussed with you prior to the treatment. 

This is a four-part treatment; each session is had 7 to 10 days apart. Each of the four sessions is an important part of the treatment process and your entire treatment will not be complete until the session is completed.

  • You are noticing lines and wrinkles.
  • You have skin crepiness.
  • You have skin that is lacking in elasticity.
  • Your skin is thin and lacks volume and plumpness.
  • You have dehydrated, sun damaged skin.
  • You would like to prevent early signs of skin ageing.

No. of treatments
Usually a 4-part treatment process with 7 to 10 days between sessions.

Procedure time
Usually 30 minutes.

Discomfort level
Very mild.

Recovery time
Very little evidence that procedure has taken place, skin is usually recovered within a few hours. As with all injectable treatment there is a risk of mild swelling and bruising at the site of injection.

Some changes can be noticed after the first treatment however; best results will be seen after your fourth treatment. Maintenance can be approximately every 6 months.

Approximately 6 months depending on the level of correction needed and patient lifestyle. Maintenance treatment is suggested at 4 to 7 months intervals post treatment.

Resume usual activities
Immediately for most activities. Avoid swimming for 48 hours and extreme temperatures for 7 days. Avoid massaging the area treated for 24 hours. Full aftercare will be provided prior to treatment.

45 Minutes

Sunekos 200 – application of one ampoule £ 195 (Each subsequent treatment in the series 10% discount £ 175)

Sunekos 1200 – application of one ampoule £ 225 (Each subsequent treatment in the series 10% discount- £ 200)

Sunekos 200 and Sunekos 1200 combined therapy – application of one ampoule of Sunkeos 200 plus application of one ampule of Sunekos 1200 £ 310 (Each subsequent treatment in the series 10% discount – £ 280)

Price List

Profhilo

  • Neck £500.00

    2 x 45 minute treatments, 4 weeks apart

  • Face £500.00

    2 x 45 minute treatments, 4 weeks apart

  • Top up (within 6 months) £200.00 per vial

    45 minute treatment

NucleoFILL

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  • NucleoFILL Medium application of one ampoule £195.00

    45 minute treatment

    Each subsequent treatment in the series benefits from a 10% discount - £175.00

  • NucleoFILL Strong application of one ampoule £225.00

    45 minute treatment

    Each subsequent treatment in the series benefits from a 10% discount - £200.00

  • NucleoFILL Medium and NucleoFILL Strong combined therapy £310.00

    Application of one ampoule of NucleoFILL Medium plus application of one ampule of NucleoFILL Strong.

    Each subsequent treatment in the series benefits from a 10% discount - £280.00

Some patients may require combination therapy, i.e. the Strong dose is applied to the middle of the face and the Medium dose is applied to the lower face and chin or neck. Such therapy allows for better effects and simultaneous treatment of the face and neck.

Sunekos

  • Sunekos 200 - application of one ampoule £195.00

    45 minute treatment

    Each subsequent treatment in the series benefits from a 10% discount - £175.00

  • Sunekos 1200 - application of one ampoule £225.00

    45 minute treatment

    Each subsequent treatment in the series benefits from a 10% discount - £200.00

  • Sunekos 200 and Sunekos 1200 combined therapy £310.00

    Application of one ampoule of Sunkeos 200 plus application of one ampule of Sunekos 1200

    Each subsequent treatment in the series benefits from a 10% discount - £280.00